Home > Faculties > Hahn, Tae Ryong

Hahn, Tae Ryong
Professor, Biochemistry Lab.
Tel: 82-31-201-2155
E-mail: trhahn@khu.ac.kr

BS, Seoul National Univ., Agricultural Chemistry (1968-1972)
MS, Korea Advanced Institute of Science, Biochemistry (1974-1976)
Ph.D., Texas Tech Univ., Biochemistry (1979-1983)
Postdoc, Yale University, Molecular Biophysics and Biochemistry (1983-1985)
Professor, Kyung Hee Univ., Genetic Engineering (1985-present)
Director, Kyung Hee Univ., Institute of Genetic Engineering (1995-1998)
Professor and Chair, Kyung Hee Univ., Graduate School of Biotechnology (1999-2006)
Director, Kyung Hee Univ., Plant Metabolism Research Center(SRC) (2000-present)
President, Korean Society for Applied Biological Chemistry (2007)
President, Korean Society of Photoscience (2008)

Biochemistry lab is focusing research on three fields of plant biochemistry and molecular biology, plant source-sink metabolism, light signal transduction mechanism, and plant proteome research on the basis of modern genomics and biotechnology techniques.

1. Plant source-sink metabolism.
The productivity of a plant(crop yields) is determined by source-sink relationship of plant tissues. There may be three methods to increase source capacity of plants, 1) to increase photosynthetic activity by manipulating Calvin cycle enzymes, 2) to increase transport capability by manipulating plastidic transporters, and 3) to increase sucrose concentration of cytosol by enhancing cytosolic metabolic enzymes. Our lab is working on source-sink metabolism by manipulating various enzymes and transporters in source organs to improve crop yields of higher plants.

2. Light signal transduction mechanism.
Light is used as an energy source for photosythesis as well as a signal for the plant growth and development. Phytochrome is a red/far red light phoptoreptor which percieves light to transform the signal through various signal transduction pathways. Our lab is working on the isolation of novel phytochrome interacting factors by using coimmunoprecipitation and MALDI-TOF mass spectrometry method. Isolated factors were used for in vitro and in vivo binding analysis and phenotype analysis to investigate physiological role of the proteins.

3. Plant proteome research.
We are working on isolating red and blue light signaling factors, and circadian rhythmic proteins by proteomics method through 2-D gel analysis and MALDI-TOF mass spectrometry.
1. Lim, H., Cho, M.-H., Jeon, J.-S., Bhoo, S.-H, Kwon, Y.-K. and Hahn, T.-R. (2009) "Altered Expression of Pyrophosphate:fructose-6-phosphate 1-phosphotransferase Affects to the Growth of Transgenic Arabidopsis Plants" Mol. Cells, 27, 1-10.

2. Lee, S.-K., Song, M.-Y., Seo, Y.-S., Kim, H.-K., Ko, S., Cao, P.-J., Suh, J.-P., Yi, G., Roh, J.-H., Lee, S., An, G., Hahn, T.-R., Wang, G.-L., Ronald, P., Jeon J.-S. (2009) "Rice Pi5-mediated Resistance to Magnaporthe oryzae Requires the Presence of Two CC-NB-LRR Genes " Genetics, 181, 1627-1638.

3. Cho, J.-I., Ryoo, N., Eom, J.-S., Lee, D.-W., Kim, H.-B., Jeong, S.-W., Lee, Y.-H., Kwon, Y.-K., Cho, M.-H., Bhoo, S.-H., Hahn, T.-R., Park, Y.-I., Hwang, I., Shen, J., and Jeon, J.-S. (2009) "Role of the Rice Hexokinases OsHXK5 and OsHXK6 as Glucose Sensors" Plant Physiol., 149, 745-759.

4. Lee, S.-K., Jeon, J.-S., Bornke, F., Voll, L., Cho, J.-I., Gho, C.-H., Jeong, S.-W., Park, Y.-I., kim, S.-J., Choi, S.-B., Miyao, A., Hirochika, H., An, G., Cho, M.-H., Bhoo, S.-H., Sonnewald, U., and Hahn, T.-R. (2008) "Loss of Cytosolic Fructose -1,6-bisphosphatase Limits Photosynthetic Sucrose Synthesis and Causes Severe Growth Retardations in Rice (Oryza sativa)" Plant, Cell Environ., 31, 1851-1863.

5. Phee, B.-K., Kim, J.-I., Shin, D.-H., Yoo, J., Park, K.-J., Han, Y.-J., Kwon, Y.-K., Cho, M.-H., Jeon, J.-S., Bhoo, S.H., and Hahn, T.-R. (2008) A Novel Protein Phosphatase Indirectly Regulates Phytochrome Interacting Factor 3 via Phytochrome. Biochem. J., 415, 247-255.

6. Yoon, J.-M., Hahn, T.-R., Cho, M.-H., Jeon, J.-S., Bhoo, S. H., and Kwon, Y.-K.(2008) "The PHY domain is Required for Conformational Stability and Spectral Integrity of the Bacteriophytochrome from Deinococcus radiodurans" Biochem. Biophys. Res. Commu., 369, 1120-1124.

7. Lee, S.-W., Jeong, K.-S., Han, S.-W., Lee, S.-E., Phee, B.-K., Hahn, T.-R., and Ronald, P.(2008) "The Xanthomonas oryzae pv. oryzae PhoPQ Two-Component System is Required for AvrXA21 Activity, hrpG Expression, and Virulence" J. Bacteriol., 190, 2183-2197.

8. Park, D.-S., Song, M.-Y., Park, S.-K., Lee, S.-K., Lee, J.-H., Song, S.-Y., Eun, M.-Y., Hahn, T.-R., Sohn, J.-K., Yi, G., Nam, M.-H., and Jeon, J.-S. (2008) "Molecular tagging of the Bph1 locus for resistance to brown planthopper (Nilaparvata lugens Stal) through representational difference analysis" Mol. Genet. Genomics, 280, 163-172.

9. Lim, H.-M., Cho, J.-I., lee, S., Cho, M.-H., Bhoo, S.-H., An., G., Hahn, T.-R., and Jeon, J.-S.(2007) "Identification of a 20-bp Regulatory Element of the Arabidobsis Pyrophosphate:Fructose-6-phosphate 1-Phosphotransferase alpha 2 Gene that is Essential for Expression" Plant Cell Rep., 26, 683-692.

10. Lee, S.-K., Hwang, S.-K., Kang, H.-G., Han, Y., Choi, S.-B., Cho, M.-H., Bhoo, S.-H., An, G.., Hahn, T.-R., and Jeon, J.-S.(2007) "Identification of the ADP-glucose Pyrophosphorylase Isoforms Essential for Starch Synthesis in the Leaf and Seed Endosperm of Rice(Oryza sativa L.)" Plant Mol. Biol., 65, 531-546.

11. Ryoo, N., Yu, C., Park, C.-S., Baik, M.-Y., Park, I., Cho, M.-H., Bhoo, S.-H., An, G., Hahn, T.-R., and Jeon, J.-S.(2007) "Knockout of a Starch Synthase Gene OsSSIIIa/Flo5 Causes White-core Floury Endosperm in Rice(Oryza sativa L.)" Plant Cell Rep., 26, 1083-1095.

12. Phee, B.-K., Park, S., Cho, J.-H., Jeon, J.-S., Bhoo, S.-H., and Hahn, T.-R.(2007) "Comparative Proteomic Analysis of Blue Light Signalling Components in the Arabidodsis Cryptochrome 1 Mutant" Mol. Cells, 23, 154-160.

13. Ryu, H.-S., Han, M., Lee, S.-K., Cho, J.-I., Ryoo, N., Heu, S., Lee, Y.-H., Bhoo, S. H., Wang, G.-L., Hahn, T.-R., and Jeon, J.-S.(2006) "A Comparative Expression Analysis of the WRKY Gene Superfamily in Rice Plants during Defense Response" Plant Cell Rep., 25, 836-847.

14. Cho, J.-I., Ryoo, N., Ko, S., Lee, S.-K., Lee, J., Jung, K.-H., Lee, Y.-H., Bhoo, S. H., Winderrickx, J., An, G., Hahn, T.-R., and Jeon, J.-S.(2006) "Structure, Expression, and Functional Analysis of the Hexokinase Gene Family in Rice(Oryza sativa L.)" Planta, 224, 598-611.

15. Phee, B.-K., Shin, D. H., Cho, J.-H., Kim, S.-H., Kim, J.-I., Lee, Y.-H., Jeon, J.-S., Bhoo, S. H., and Hahn, T.-R.(2006) "Identification of Phytochrome-interating Protein Candidates in Arabidopsis thaliana by Co-immunoprecipitation Coupled with MALDI-TOF MS" Proteomics, 6, 3671-3680.

16. Lee, J.-W., Lee, D.-S., Bhoo, S.-H., Jeon, J.-S., Lee, Y.-H., Hahn, T.-R.(2005) "Transgenic Arabidopsis Plants Expressing E. coli Pyrophosphatase Display both Altered Carbon Partitioning in Their Source Leaves and Reduced Photosynthetic Activity" Plant Cell Rep., 24, 374-382.

17. Cho, J.-I., Lee, S.-K., Ko, S., Kim, H.-K., Jun, S.-H., Lee, Y.-H., Bhoo, S.-H., Lee, K.-W., An, G., Hahn, T.-R., Jeon, J.-S.(2005) "Molecular Cloning and Expression Analysis of the Cell-wall Invertase Gene Family of Rice(Oryza sativa L.)" Plant Cell Rep., 24, 225-236.

18. Phee, B.-K., Cho, J.-H., Park, S., Jung, J. H., Lee, Y.-H., Jeon, J.-S., Bhoo, S.-H., and Hahn, T.-R.(2004) "Proteomic Analysis of the Response of Arabidopsis Chloroplast Proteins to High light Stress" Proteomics, 4, 3560-3568.

19. Yi, G., Lee, S.-K., Hong, Y.-K., Cho, Y.-C., Nam, H.-M., Kim, S.-C., Han, S.-S., Wang, G.-L., Hahn, T.-R., Ronald, P.-C., and Jeon, J.-S.(2004) "Use of Pi5(t) Markers in Marker-assisted Selection to Screen for Cultivars with Resistance to Magnaporte grisea" Theor. Appl. Genet., 109, 978-985.

20. Choi, G., Yi, H., Lee, J., Kwon, Y.-K., Soh, M.-S., Shin, B., Luka, Z., Hahn, T.-R., and Song, P.-S.(1999) "Phytochrome Signalling is Mediated through Nucleotide Diphosphate 2" Nature, 401, 610-613.