Our researches in the Laboratory of Food Microbiology & Biotechnology (LFMB) are focused on the molecular biological and biotechnological studies of various food microorganisms and their applications in food-related industries.

Our lab always welcomes students who are eager to be a young scientist with Fundamental logic, Magnificent dream, and Big heart (FMB).

- Expression, production, and application of carbohydrate active enzymes using GRAS level microorganisms.
- Production of various high value-added functional bio-materials including isoflavones and ginsenosides by transglycosylational modification via various carbohydrate active enzymes.
- Metabolic engineering of various fungal strains such as Aspergillus oryzae, a famous fungus in traditional Korean foods and Aspergillus terreus, an antihypercholesterolemic agent producing fungus.

1. Cha J, Jung JH, Park SE, Cho MH, Seo DH, Ha SJ, Yoon JW. Lee OH. Kim YC. Park CS. Molecular cloning and functional characterization of a sucrose isomerase (isomaltulose synthase) gene from Enterobacter sp. FMB-1. J. Appl. Microbiol (2009) 107(4):1119-1130.

2. Lee OH. Lee BY., Lee J. Lee HB, Son JY, Park CS, Shetty K, Kim YC. Assessment of phenolics-enriched extract and fractions of olive leaves and their antioxidant activities. Bioresour Technol. (2009) 100(23):6107-6113.

3. Cho KH, Auh JH, Ryu JH, Kim JH, Park KH, Park CS, Yoo SH. Structural modification and characterization of rice starch treated by Thermus aquaticus 4-glucanotransferase. Food Hydrocolloids (2009) In press

4. Choi KH, Seo JY, Park KM, Park CS, Cha JH. Characterization of glycosyl hydrolase family 3 β-N-acetylglucosaminidases from Thermotoga maritima and Thermotoga neapolitana. J. Biosci. Bioeng (2009) In press

5. Nguyen VD, Min BC, Kyung MO, Park JT, Lee BH, Choi CH, Seo NS, Kim YR, Ahn DU, Lee SJ, Park CS, Kim JW, Park KW. Identification of a naturally-occurring 8-[D-glucopyranosyl-(1→6)-β-D-glucopyranosyl] daidzein from cultivated Kudzu Root. Phytochem. Anal. (2009) In press

6. Ha SJ, Seo DH, Jung JH, Cha JH, Kim TJ, Kim YW, Park CS. Molecular cloning and functional expression of a new amylosucrase from Alteromonas macleodii. Biosci. Biotechnol. Biochem. (2009) 73;1505-1512

7. Shim JH, Park JT, Hong JS, Kim JW, Kim MJ, Auh JH, Kim YW, Park CS, Boos W. Kim JW, Park KH. Role of maltogenic amylase and pullulanase in maltodextrin and glycogen metabolism of Bacillus subtilis 168. J. Bacteriol. (2009) 191;4835-4844.

8. Jung JH, Seo DH, Ha SJ, Song MC, Cha JH, Yoo SH. Kim TJ. Baek NI, Baik MY. Park CS. Enzymatic synthesis of salicin glycosides through transglycosylation catalyzed by amylosucrases from Deinococcus geothermalis and Neisseria polysaccharea. Carbohydr. Res. (2009) 344;1612-1619.

9. Seo DH, Jung JH, Ha SJ, Song MC, Cha JH, Yoo SH, Kim TJ, Baek NI, Park CS. Highly selective biotransformation of arbutin to arbutin-glucoside using amylosucrase from Deinococcus geothermalis DSM 11300. J. Mol. Cata. B: Enzym (2009) 60;113-118.

10. Choi HS, Kim HS, Park CS, Kim BY, Baik MY, Ultra high pressure (UHP)-assisted acetylation of corn starch. Carbohydr. Poly. (2009) 78;862-868.

11. Lee OH, Kwon YI, Hong HD, Park CS, Lee BY, Kim YC. Production of reactive oxygen species and changes in antioxidant enzyme activities during differentiation of 3T3-L1 adipocyte. J. Korean Soc. Appl .Biol. Chem (2009) 52; 70-75

12. Lee GY, Ha SJ, Jung JH, Seo DH, Park JY, Kim SR, Park NW, Kweon DK, Park SH, Park CS. Effect of non-animal-derived nitrogen sources on the production of hyaluronic acid by Streptococcus sp. KL0188. J. Korean Soc. Appl. Biol. Chem (2009) 52; 283-289

13. Kwon GH, Lee HA, Park JY, Kim JS, Lim J, Park CS, Kwon DY, Kim YS, Kim JH. Development of a RAPD-PCR method for identification of Bacillus species isolated from Cheonggukjang. Int. J. Food Microbiol (2009) 129; 282-287

14. Park CS, Seo DH, Jung JH, Ha SJ. (2009) Method for production of -arbutin using amylosucrase from Deinococcus geothermalis. Korea Patent #10-2009-0086136

15. Moon KO, Choi KH, Kang HY, Oh JI, Jang SB, Park CS, Lee JH, Cha J. Probing the critical residues for intramolecular fructosyl transfer reaction of a levan fructotransferase. J. Microbial. Biotechnol (2008) 18; 1064-1069

16. Jung JH, Seo DH, Bhoo SH, Ha SJ, Kim JS, Kim JH, Kwon DY, Cha J, Park CS. Use of restriction fragment length polymorphism analysis to differentiate fungal strains in Sunchang Meju. Food. Sci. Biotechnol (2008) 17; 888-891

17. Choi KW, Park KM, Jung SY, Park CS, Park KW, Cha JH, Modulation of the regioselectivity of a Thermotoga neapolitana β-Glucosidase by site-directed mutagenesis. J. Microbial. Biotechnol (2008) 18:901-907

18. Jang CH, Park CS, Lim JK, Kim JW, Kwon DY, Kim YS, Shin DH, Kim JS. Metabolism of isoflavone derivatives during manufacturing of traditional Meju and Doenjang. Food. Sci. Biotechnol (2008) 17:442-445

19. Chun J, Jeong WJ, Kim JS, Lim J, Park CS, Kwon DY, Choi I, Kim JH. Hydrolysis of isoflavone glucosides in soymilk fermented with single or mixed cultures of Lactobacillus paraplantarum KM, Weissella sp. 33, and Enterococcus faecium 35 isolated from humans. J. Microbiol. Biotechnol (2008) 18:573-578

20. Park CS, Seo DH, Jung JH, Ha SJ, Cha J, Yoo SH, (2008) Method for preparing of single arbutin derivative by using amylosucrase from Deinococcus geothermalis and the derivatives thereof. Korea Patent #10-2009-0081491