Home > Faculties > Baek, Nam In

Baek, Nam In
Professor, Natural Products Chemistry Lab.
Tel: 82-31-201-2610
E-mail: nibaek@khu.ac.kr
BS, Seoul National Univ., Agricultural Chemistry (1975-1976)
Researcher, Nongshim Foods Manufacturing Co. Ltd. (1979-1981)
MS, Seoul National Univ., Plant Physiology (1981-1983)
Ph.D., Osaka National Univ., Natural Products Chemistry (1985-1989)
Researcher, National Institute of Agricultural Science & Technology (1981-1982)
Senior Researcher, Korea Ginseng & Tabacco Research Institute (1983-2006)
Post Doctor, University of Illinois at Chicago (1992-1993)
Professor, Kyung Hee Univ., Oriental Medicinal Materials & Processing (1996-present)
Professor, Kyung Hee Univ., Graduate School of Biotechnology (1998-present)
Visiting Professor, UC Davis (2006-2007)

- To search for biologically active materials from natural sources.
- To isolate and purify active compounds from natural sources through solvent extraction, systematic fractionation, column chromatography, HPLC and synthesis of derivatives.
- To determine the chemical structure of isolated compounds using chemical and spectroscopic methods including NMR, MS, and IR.
- To develop the procedure for mass-production of active compounds through chemical synthesis, biological transformation, and to develop functional foods, drug materials, and functional cosmetics.
- To perform metabolites analysis of natural cells, target analysis, and metabolomics study using LC/MS, GC/MS, and LC/NMR. Finally to establish a network between metabolites and to construct systems biology in the living cells.
1. Song MC, Yang HJ, Cho JK, Chung IS, Kwon MM, Kim DK, Baek NI (2009) Glycerides from the Aerial Parts of Garland (Chrysanthemum coronarium L.) and Their Inhibitory Effects on ACAT, DGAT, FPTase, and b-Secretase. Food Science and Biotechnology 18(1):95-102.

2. Lee DY, Jung LK, Lyu HN, Jeong TS, Lee YH, Baek NI (2009) Triterpenoids from the Fruits of Cornus kousa Burg. as Human Acyl-CoA: Choresterol Acyltransferase Inhibitors. Food Science and Biotechnology 18(1):223-227.

3. Song MC, Yang HJ, Lee DG, Kim DK, Ahn EM, Woo YM, Baek NI (2009) Glycosyldiglycerides from the Aerial Parts of Garland (Chrysanthemum coronarium). Journal of the Korean Society for Applied Biotechnology Chemistry 52(1):88-91.

4. Cho JG, Lee DY, Lee JW, Lee DG, Lee YH, Kim SY, Kim SH, Baek NI (2009) Acyclic Diterpenoids from the Leaves of Capsicum annuum. Journal of the Korean Society for Applied Biological Chemistry 52(2):128-132.

5. Han JM, Kim MJ, Baek SH, An SJ, Jin YY, Chung HG, Baek NI, Choi MS, Lee KT, Jeong TS (2008) Antiatherosclerotic Effects of Artemisia princeps Pampanini cv. Sajabal in LDL Receptor Deficient Mice. Journal of Agricultural and Food Chemistry 57(4):1267-1274.

6. Yun KJ, Shin JS, Choi JH, Back NI, Chung HG, Lee KT (2009) Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE2, and pro-inflammatory cytokines production via the down-regulation of NF-κB in RAW 264.7 murine macrophage cells. International Immunophamacology 9:1323-1331.

7. Song MC, Nigussie F, Yang HJ, Lee DY, Kim HH, Chung DK, Baek NI (2008) Phenolic Glycosides from the Roots of Lindera fruticosa and Their Inhibitory Activi ty on Osteoclast Differentiation. Chemical & Pharmaceutical Bulletin 56(5):707-710.

8. Song MC, Yang HJ, Park SK, Choi HK, Baek NI (2008) A New Sterol from Whole Plants of Eriocaulon sieboldianum. Bulletin Korean Chemical society 29(3):669-671.

9. Bang MH, Han MW, Song MC, Cho JG, Chung HG, Jeong TS, Lee KT, Choi MS, Kim SY, Baek NI (2008) A Cytotoxic and Apoptosis-Inducing Sesquiterpenoid Isolated from the Aerial parts of Artermisia princeps PAMPANINI(SAJABALSUK). Chemical & Pharmaceutical Bulletin 56(8):116-1172.

10. Song MC, Yang HJ, Kim DK, Baek NI (2008) A New Acyclic Diterpene from Trigonotis peduncularis. Bulletin Korean Chemical society 29(11):2267-2269.

11. Song MC, Yang HJ, Jeong TS, Kim KT, Baek NI (2008) HeterocyclicCompounds from Chrysanthemum coronarium L. and Their Inhibitory Activity on hACAT-1, hCAT-2, and LDL-Oxidation. Archives of Pharmacal Research 31(5):573-578.

12. Yoo JS, Ahn EM, Song MC, Bang MH, Kim DH, Han MW, Kwak HY, Lee DY, Lyu HN, Baek NI (2008) Quantitative Analysis of Coumarins from Angelica gigas Using H-NMR. The Korean Society of Food Science and Biotechnology (17)3:573- 577.

13. Lee DY, Yoo KH, Chung IS, Kim JY, Chung DK, Kim DK, Kim SH, Baek NI (2008) A New Lignan Glycoside from the Fuits of Cornus kousa Burg. Archives of Pharmacal Research (31)7:830-833.

14. Lee DY, Han KM, Song MC, Lee DG, Rho YD, Baek NI (2008) A New Lignan glycoside from the rhizomes of Imperata cylindrica. Journal of Asian Natural Products Research (10)4:299-302.

15. Nam SJ, Joo SB, Kim SH, Baek NI, Choi HK, Park SK (2008) Induces Metabolite Changes in Myriophyllum spicatum During Co-existence Experiments with the Cyanobacterium Micarocystis aeruginosa. Journal of Plant Biology 51(5):373-378.

16. Lyu HN, Lee DY, Kim DH, Yoo JS, Lee MK, Kim IH, Baek NI (2008) Phenolic Compounds from the Fruit Body of Phellinus linteus Increse Alkaline Phosphatase (ALP) Activity of Human Osteoblast-like Cells. The Korean Society of Food Science and Biotechnology 14(6):1214-1220.

17. Jung SJ, Kim DH, Hong YH, Lee JH, Song HN, Rho YD, Baek NI (2007) Flavonoids from the Flower of Rhododendron yedoense var. Poukhanense and Their Antioxidant Activities. Archives of pharmacal research 30(2) p.146-150.

18. Han JT, Lee SY, Lee YH, Baek NI (2007) Antioxidative Diarylheptanoids from the Fruits of Alpinia oxyphylla. Food Sci. Biotechnol 16(6):1060-1063.

19. Song MC, Nigussie F, Yang HJ, Baek NI (2007) A New Benzophenone from Lindera fruticosa. Bull. Korean Chem. Soc. 28(7):1209-1210.

20. Kim DH, Han KM, Bang MH, Lee YH, Chung IS, Kim DK, Kim SH, Kwon BM, Park MH, Baek NI (2007) Cyclohexylethanoids from the Flower of Campsis grandiflora. Bull. korean Chem. Soc. 28(10):1851-1853.